

INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stemcell model.
1. 논문 제목: INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model. 2. 저자명: Patrick A. DeSouza, Matthew Ishahak, Xuan Qu, Colin McCornack, Devi Annamalai, Diane D.Mao, Rajanikanth Vangipurapu, Yiwei Fu, Alexandre T. Vessoni, Ryan T. Cleary, Rowland H. Han, Punn Augsornworawat, Timothy Woodiwiss, Darby Agovino, Braxton Sizemore, Jessica Kline, Maryam Borhani-Haghighi, Hao Chen, Sangami Pugazenthi, Hiroko Yano, TingWang, Luis F. Z. Batista
김소영
4일 전4분 분량


Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models.
논문 제목 : Adoptive cell therapy with macrophage-drug conjugates facilitates cytotoxic drug transfer and immune activation in glioblastoma models. 저자명 : Miaomiao Sun, Maciej Bialasek, Maud Mayoux, Meng-Syuan Lin, Alicia Buck, Ilona Marszałek, Bartłomiej Taciak, Marcel Bühler, Małgorzata Górczak, Paulina Kucharzewska, Daria Kurpiel, Małgorzata Siemińska, Julia Nowakowska Brancewicz, Konrad Gabrusiewicz, Waldemar Lipiński, Sibylle Pfammatter, Steve Pascolo Gregor Hutter, Lubomi
지우 이
4일 전3분 분량


Allosteric role of a structural NADP+ molecule in glucose-6-phosphate dehydrogenase activity.
논문 제목 : Allosteric role of a structural NADP+ molecule in glucose-6-phosphate dehydrogenase activity. 저자명 : Xuepeng Wei, Kathryn Kixmoeller c, Elana Baltrusaitis c, Xiaolu Yang d, Ronen Marmorstein Publish : 2022, Jul 12 DOI : https://doi.org/10.1073/pnas.2119695119 Abstract : Human glucose-6-phosphate dehydrogenase (G6PD) is the main cellular source of NADPH, and thus plays a key role in maintaining reduced glutathione to protect cells from oxidative stress disorders such
임지현
1월 27일4분 분량


Emerging Therapies for Glioblastoma
AlissaA.Thomas,MD;CameronW.Brennan,MD;LisaM.DeAngelis,MD;AntonioM.Omuro,MD IMPORTANCE Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the prognosis is poor, with a median survival of 16 to 19 months and poor quality of life throughout the disease course. New treatments are needed. EVIDENCE REVIEW Articles were identified through a search of PubMed references from March
소영 정
1월 26일2분 분량


Unraveling the nexus: Genomic instability and metabolism in cancer
Gujar, Vaibhavi et al. Cell Reports, Volume 44, Issue 4, 115540 The DNA-damage response (DDR) is a signaling network that enables cells to detect and repair genomic damage. Over the past three decades, inhibiting DDR has proven to be an effective cancer therapeutic strategy. Although cancer drugs targeting DDR have received approval for treating various cancers, tumor cells often develop resistance to these therapies, owing to their ability to undergo energetic metabolic repr
한울 전
1월 22일3분 분량


Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma.
1. 논문 제목: H uman cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma. 2. 저자명: Brett W. Stringer, Manam Inushi De Silva1, Zarina Greenberg, Alejandra Noreña Puerta1, Robert Adams, Bridget Milky, Michael Zabolocki, Mark van den Hurk, Lisa M. Ebert, Christine Fairly Bishop, Simon J. Conn, Ganessan Kichenadasse, Michael Z. Michael, Rebecca J. Ormsby, Santosh Poonoose, Cedric Bardy 3. 출처 및 게재 (발행일): Science Advanced, 25 Octobe
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1월 13일2분 분량








