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1.논문 제목: Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer. 2.저자명: Jingbo Li, Jiao Liu, Zhuan Zhou, Runliu Wu, Xin Chen, Chunhua Yu, Brent Stockwell, Guido Kroemer, Rui Kang, Daolin Tang. 3.Publish: Science Translational Medicine, 1 November, 2023 4.DOI: 10.1126/scitranslmed.adg3049 5.Abstract: Current ferroptosis inducers effectively kill cancer cells by inhibiting GPX4 but also damage immune cells, limiting their...

1.논문 제목: NRF2 promotes ferroptosis sensitivity in temozolomide-resistant glioblastoma cells through MRP1/ABCC1 regulation 2.저자명: Isabela de Souza, Luiza K. S. Moreira, Camila B. Gomes, Marina T. Andrade, Bruna C. Carvalho, Mariana M. Silva, Bruno F. M. M. Pereira, Mariana T. Latancia, Daniela Menck, Marcelo Lancellotti, Luiz R. G. Gomes, C. R. R. Rocha 3.Publish: July 1, 2022 4.DOI: 10.1038/s41419-022-05044-9 5.Abstract: Glioblastoma frequently develops resistance to temozolomide (TMZ),...

1.논문 제목: Microglial SRGN aggravates neuroinflammation after ischemic stroke via interacting with CD44 2.저자명: Yi Qian, Lixuan Yang, Jian Chen, Na Zhang, Yuting Gu, Xiaofei Bao, Shuxuan Xie, Hai Yu, Yanchun Chen, Chao Zhao, Yun Xu 3.출처 및 게제일: Journal of Neuroinflammation, 29 January 2024 4.DOI: http://dio.org/10.1186/s12974-024-03026-6. 5.Abstract: Ischemic stroke triggers severe neuroinflammation driven largely by activated microglia. This study investigated the role of Serglycin (SRGN) using...