

Pharmacogenomics of GPCR Drug Targets
Alexander S. Hauser, Sreenivas Chavali, Ikuo Masuho, Leonie J. Jahn, Kirill A. Martemyanov, David E. Gloriam, M. Madan Babu 11 January...
임지현
2025년 9월 23일3분 분량


Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin
Pan F. Chan, Velupillai Srikannathasan, Jianzhong Huang, Haifeng Cui, Andrew P. Fosberry, Minghua Gu, Michael M. Hann, Martin Hibbs, Paul...
한울 전
2025년 9월 16일3분 분량


Brain tumoroids: Treatment prediction and drug development for brain tumors with fast, reproducible, and easy-to-use personalized models
Aurélie Soubéran, Carine Jiguet-Jiglaire, SolineToutain, Philippe Morando, Nathalie Baeza-Kallee , Romain Appay, Céline Boucard, Thomas...
차혜욱
2025년 9월 11일2분 분량


Choroid plexus mast cells drive tumor-associated hydrocephalus
Yiye Li, Can Di, Shijian Song, Yubo Zhang, Yiwen Lu, Jianyou Liao, Bingxi Lei, Jian Zhong, Kaihua Guo, Nu Zhang, and Shicheng Su Cell...
김소영
2025년 9월 8일2분 분량


Cerebrospinal fluid markers of neuroinflammation and coagulation in severe cerebral edema and chronic hydrocephalus after subarachnoid hemorrhage: a prospective study
Yuanjian Fang, Yibo Liu, Luxi Chen, Junjie Wang, Jiahao Zhang, Haocheng Zhang, Sixuan Tian, Anke Zhang, Jianmin Zhang, John H. Zhang,...
이지우
2025년 9월 8일3분 분량


Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery
Timothy B. Callis, Taylor R. Garrett, Andrew P. Montgomery, Jonathan J. Danon, Michael Kassiou* 10.1021/acs.jmedchem.2c00969 abstract The...
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2025년 9월 3일3분 분량


Effective targeting of PDGFRA-altered high-grade glioma with avapritinib
Lisa Mayr, Sina Neyazi, Kallen Schwark, ..., Carl Koschmann, Johannes Gojo, Mariella G. Filbin Cancer Cell. 2025 Apr 14;43(4):740-756.e8...
한울 전
2025년 9월 3일3분 분량


Neutrophil extracellular trap-mediated impairment of meningeal lymphatic drainage exacerbates secondary hydrocephalus after intraventricular hemorrhage
Qiang Zhang, Yujie Chen, Yingpei Li, Zhou Feng, Liang Liang, Xiaoke Hao, Wenbo Kang, Zhaoqi Zhang, Xuyang Zhang, Rong Hu, Hua Feng, Zhi...
김소영
2025년 8월 18일2분 분량


Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways.
Hao-Xiang Wang, Zi-Ang Deng, Yuan-You Li, Jun Li, Ya-Xing Chen, Yan-Jie Zhao, Ke-Ru Huang, Wei- Ning Tian, Ai-Ping Tong, and...
이지우
2025년 8월 18일2분 분량


Integrated proteogenomic characterization of glioblastoma evolution
Kyung-Hee Kim, Simona Migliozzi, Harim Koo, ..., Do-Hyun Nam, Antonio Iavarone, Jong Bae Park 2024, Cancer Cell 42, 358–377 DOI: ...
차혜욱
2025년 8월 18일2분 분량


Recent advances in AI-driven protein-ligand interaction predictions
Jaemin Sim, Dongwoo Kim, Bomin Kim, Jieun Choi and Juyong Lee 24 February 2025 https://doi.org/10.1016/j.sbi.2025.103020 Structure-based...
임지현
2025년 8월 11일3분 분량


Extrachromosomal DNA: An Emerging Hallmark in Human Cancer
Sihan Wu,1 Vineet Bafna,2 Howard Y. Chang,3 and Paul S. Mischel4,5 Annu. Rev. Pathol. Mech. Dis. 2022. 17:367–86...
한울 전
2025년 8월 8일3분 분량


Molecular signatures of normal pressure hydrocephalus: a large-scale proteomic analysis of cerebrospinal fluid.
Aida Kamalian, Siavash Shirzadeh Barough, Sara G. Ho, Marilyn Albert, Mark G. Luciano, Sevil Yasar Abhay Moghekar Fluids and Barriers of...
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2025년 7월 28일3분 분량


The blood–brain barrier: Structure, regulation and drug delivery
Wu, D., Chen, Q., Chen, X. Signal Transduction and Targeted Therapy volume 8, Article number: 217 (2023) https://doi.org/10.1038/s41392-0...
차혜욱
2025년 7월 21일2분 분량


Therapeutic approaches targeting the neurotensin receptors
Malliga R. Iyer and George Kunos Expert Opin Ther Pat . 2021 May;31(5):361-386 DOI: 10.1080/13543776.2021.1866539 Abstract Introduction:...
임지현
2025년 7월 21일3분 분량


The changing landscape of medicinal chemistry optimization
Anita Rácz, Levente M. Mihalovits, Maximilian Beckers, Nikolas Fechner, Nikolaus Stiefl, Finton Sirockin, William McCoull, Emma...
한울 전
2025년 7월 18일3분 분량


Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies
Alberto Visioli1†, Nadia Trivieri2†, Gandino Mencarelli2 , Fabrizio Giani1 , Massimiliano Copetti3 , Orazio Palumbo4 , Riccardo Pracella2...
차혜욱
2025년 7월 7일3분 분량


RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus.
Xue Pang1, Lin Gu1, Qiu-Ying Han, Jia-Qing Xing, Ming Zhao, Shao-Yi Huang, Jun-Xi Yi, Jie Pan, Hao Hong Wen Xue, Xue-Qing Zhou, Zhi-Hui...
이지우
2025년 7월 7일3분 분량


The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
Stephanie M. Robert, Benjamin C. Reeves, Emre Kiziltug, Phan Q. Duy, Jason K. Karimy, M. Shahid Mansuri, Arnaud Marlier, Garrett...
김소영
2025년 7월 7일2분 분량


Discovery of new LXRβ agonists as glioblastoma inhibitors
Hao Chen, Ziyang Chen, Zizhen Zhang, Yali Li, Shushu Zhang, Fuqiang Jiang, Junkang Wei, Peng Ding, Huihao Zhou, Qiong Gu, Jun Xu 2020 May...
임지현
2025년 6월 30일3분 분량




